2 or more cursors?

I would like to control 2 or more cursors to click on different items on the screen, is this possible?

 

I've been able to do things like use a touchpad and a mouse at the same time, but never with 2 cursors.
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A perusal of the Windows API makes me say 'no, or at least with fairly odd/unusable results'. The common functions for interacting with the cursor are built around a single cursor. A click event, however, can be triggered from any location (ie, the cursor location doesn't matter), so there may be third party software that will emulate additional cursors controlled by extra pointing devices.